20 NDC - Detalhes da reação entre o peroxinitrito e PDI
Doenças como o mal de Alzheimer, de Parkinson, e catarata ocular estão associadas ao fato de as proteínas das células perderem sua estrutura. Com isso, formam agregados que são tóxicos. Esse processo pode ser desencadeado por oxidantes biológicos, isto é, moléculas capazes de captar elétrons das proteínas, o que leva a mudanças em sua estrutura. Pesquisadores do Centro de Pesquisa sobre Processos Redox em Biomedicina (Cepid Redoxoma), sediado no Instituto de Química da USP, estudaram os detalhes da reação entre um desses oxidantes biológicos, o peroxinitrito, e a proteína PDI - que se agrega quando encontra o peroxinitrito.
Title overview
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السنة
2018
المدة
10m
IMDb
0
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